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CDK7 抗体 (C-Term)

This anti-CDK7 antibody is a 小鼠 单克隆 antibody detecting CDK7 in WB, IP, IF, IHC (fro) 和 FACS. Suitable for 人.
产品编号 ABIN452138
发货至: 中国

Quick Overview for CDK7 抗体 (C-Term) (ABIN452138)

抗原

See all CDK7 抗体
CDK7 (Cyclin-Dependent Kinase 7 (CDK7))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CDK7 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS)

克隆位点

MO-1-1
  • 抗原表位

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    C-Term

    特异性

    Mo-1.1 recognizes the key cell cycle regulator cdk7, which is essential to activate the cdk2 kinase in G1 phase and the cdc2 kinase in G2/M phase.

    产品特性

    Synonyms: CAK1, P39 Mo15, STK1, CDK-activating kinase, Cell division protein kinase 7, TFIIH basaltranscription factor complex kinase subunit, 39 kDa protein kinase

    纯化方法

    Protein A affinity chromatography

    免疫原

    Recombinant C-terminal 221 aa fragment of human wild-type cdk7/CAK (cyclin activatingkinase)

    亚型

    IgG2b
  • 应用备注

    Immunohistochemistry of frozen sections: 1/10 - 1/20, 1h at RT. Immunofluorescence. Immunoprecipitation of active kinase complex. Cell sorting (FACS analysis). Immunoblotting.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Restore in 1 mL dist. water (final solution contains 0.09 % NaN3, 0.5 % BSA in PBS buffer, pH 7.4).

    储存条件

    4 °C/-20 °C

    储存方法

    Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    CDK7 (Cyclin-Dependent Kinase 7 (CDK7))

    别名

    CDK7

    背景

    Cdk7 is a member of the cyclin dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. Cdk7 forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.Synonyms: 39 kDa protein kinase, CAK1, CDK-activating kinase, Cell division protein kinase 7, P39 Mo15, STK1, TFIIH basal transcription factor complex kinase subunit

    基因ID

    1022

    UniProt

    P50613

    途径

    Cell Division Cycle, DNA Damage Repair, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, M Phase
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